Glipizide || Understanding Medicine of diabetes

This article is specifically for Type 2 diabetics.
If you are suffering from this disease, there is a great chance that you must be taking some form of pill.
These pills are used widely around the world and are of great help to manage the blood sugar.

You must be taking these pills one or twice a day.
But do you know how it functions?
Are you aware of its side-effects?

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Most of the people i know are completely unaware of the kind of drugs they are taking.
They are completely dependent on their doctors.
With the rising numbers of patients and the skewed ratio of doctors availability, it is imperative to make yourself aware of the kind of treatment we are taking.

With this article, i have made an effort to make you understand about one of the common medicine used by Type 2 diabetics known as Glipizide.


What is Glipizide?
It belongs to group of drugs known as Sulfonylureas.
It reacts with the Beta cells of pancreas to produce more insulin.
Keep in mind that Glipizide works only if you have effective Beta cells present in your body. In case of Type 1 diabetes, the beta cells are completely destroyed, hence there is no scope of using this medicine.

Suggested Reading: Side Effect of Sulfonylureas


How to take Glipizide?
Usually people take this pill once a day 30 minutes before their first meal.
But there are people who need more than one dose to manage their blood sugar, you have to talk to the doctor to sort this out as per your requirement.

In order to prevent the side effect, the doctor start with low dose of Glipizide and then increase it as your body gets accustomed with the medicine.
The doctor starts with 2.5-3 mg of Glipizide and then altering the dose with the body requirement.
The maximum dose can go up to 40 mg/day.

Though you need the doctor help to get the right dose.
But with experience and daily testing, you can figure out the right amount of Glipizide for your self.

I am Type 1 diabetic myself  and i take regular insulin injections.
When i was diagnosed i was completely dependent on the doctor for insulin dosage.
But now with regular blood checkup and proper diet, i am fully aware of my insulin requirements.
This helped me to save lot of time and money from doctor consultation, now i only visit the doctor for emergency cases.
Suggested Reading: How to bring blood sugar down if over 250?




Side effects of Glipizide
You must be aware of the side-effect of the medicine you are taking.
This will make you medically alert and responsive in case of any emergency.
Below are some the side effects of Glipizide, if you face any of these please consult your doctor.

1. Upset Stomach
If you are taking high dose of Glipizide, there are chances Nausea, Diarrhea and other stomach issues.

2. Skin Rashes and Blisters

3. Headache and Dizziness
If you face drowsiness, make sure you sit comfortably in one place and do not drive.

4. Weight Gain
Like people who start taking insulin face weight gain, the effect is only visible among people taking Glipizide.

5. Increased risk of Heart Disease

Suggested Reading: Diabetes & Heart Disease


1. Type 1 diabetics should not take this medicine.
Many people around the world are misdiagnosed as Type 2 in their initial phase and were give Glipizide to control the blood sugar.
When you get diagnosed with diabetes, make suitable test to confirm whether it is Type 1 or Type 2. Medicines like Glipizide do not work on patient suffering from Type 1.

2. Severe Hypoglycemia
Hypoglycemia is a condition of low blood sugar.
You face this condition when your blood sugar goes below 78 mg/dl. Dizziness, confusion, shakiness are some of its symptoms.
This condition is extremely dangerous and can lead to loss of life.

Patients taking Glipizide should take proper meal.
I have come across patient who take the pill and then forget to eat their meal. Please don’t do this mistake, if you take the pill, make sure to eat throughout the day.

3. Reaction with other medicines
The effect of glipizide could be enhance by drugs like antibiotics, Warfarin, Sulfonamides etc.
If you are taking any other medicines, monitor your blood sugar frequently and consult your doctor.

4. Pregnant women are not recommended to have Glipizide dose during their pregnancy period.
Women during these period have different insulin requirement and there is also a worry that the effect of medicine can also affect the breast milk.
If you are pregnant or lactating mother, consult your doctor about this condition.

5. People suffering from Kidney or Liver disorder need calculated dose of the medicines.
These people may face greater hypoglycemic effects so they have monitor the dose appropriately.
Suggested Reading: Hypoglycemia vs Hyperglycemia


Effectiveness of Glipizide
1. Diabetes is a complex problem.
You will face situation when you find that drugs is not giving great control over your blood sugar.
While on other days, only a small dose gives you perfect control.

That is why it is very important to check blood sugar frequently.
2. The effectiveness of Glipizide usually lasts for 24 hours.
So make sure you eat your meal in between.
Not eating can lead to Hypoglycemia episode.

3. Avoid Drinking Alcohol
Alcohol can make your blood sugar go low. If you are still planning to drink, please be cautious and keep some kind of sugar candies in your pocket.
Suggested Reading: Diabetes and Alcohol


Final Word
I have always said that the best way to manage your diabetes and reduce the medicine dosage is by eating low carbohydrate foods. You need to understand that it is the carbohydrates which cause increase in blood sugar. If you start taking low carb foods, half of the problem is solved.



Further Reading
Metformin Side effect in Men
Diabetes and Viagra
Viagra Side Effects in Men

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